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Mutations in the leptin-melanocortin pathway and weight loss after bariatric surgery: a systematic review and meta-analysis

Semaglutide targets the main causes of weight gain, making it an excellent option for those looking to achieve long-term weight loss success

Maximum Dose : For weight management, doses of up to 2.4 mg per week may be prescribed, though this varies based on individual health needs

Patients who combine medication with moderate dietary adjustments and physical activity consistently report better sustained weight loss than those relying solely on medication

The mechanisms proposed for this protective effect include modulation of inflammatory pathways, reduction of oxidative stress, and improvement of metabolic parameters that contribute to liver carcinogenesis (Arvanitakis et al., 2022)